4.1. Survey and Data Acquisition
Searches carried out in the databases using the keywords “human”, “whole blood”, “pbmc” and “peripheral blood” resulted in 87 potential studies. After applying the inclusion criteria defined in Section 3.1, only 12 studies were selected for analysis, as shown in Table 1.
Table 1 - List of studies selected for analysis.
*Número de Amostras Controle. Células em branco nas colunas de gênero são informações ausentes ou não informativas, como 0 ou 1.
Estudo | Base de Dados | Empresa | Plataforma | Tecido | N. Amostras* | Idade Mínima | Idade Máxima | N. Mulheres | N. Homens |
GSE73089 | GEO | Agilent | GPL4133 | PBMC | 120 | 40 | 97 | 64 | 56 |
E-TABM-305 | Array Express | Illumina | A-MEXP-691 | linfócitos | 1240 | 14 | 81 | ||
GSE15573 | GEO | Illumina | GPL6102 | PBMC | 15 | 45 | 67 | 10 | 5 |
GSE48556 | GEO | Illumina | GPL6947 | PBMC | 33 | 44 | 76 | 24 | 9 |
GSE54514 | GEO | Illumina | GPL6947 | sangue total | 36 | 24 | 70 | 24 | 12 |
GSE12288 | GEO | Affymetrix | GPL96 | sangue total | 112 | 37 | 68 | 28 | 84 |
GSE18781 | GEO | Affymetrix | GPL570 | sangue total | 25 | 22 | 83 | 20 | 5 |
GSE42057 | GEO | Affymetrix | GPL570 | PBMC | 42 | 46 | 80 | ||
GSE22255 | GEO | Affymetrix | GPL570 | PBMC | 20 | 45 | 73 | 10 | 10 |
GSE19314 | GEO | Affymetrix | GPL570 | PBMC | 20 | 34 | 70 | 15 | 5 |
GSE16028 | GEO | Affymetrix | GPL570 | sangue total | 109 | 23 | 64 | 59 | 50 |
GSE46097 | GEO | Affymetrix | GPL571 | sangue total | 63 | 41 | 80 | 36 | 27 |
The selected studies are of 3 subtypes of blood tissue, performed on 7 different microarray platforms (Figure 4.1), from 3 companies (Agilent, Illumina and Affymetrix) and totalling 1835 samples.
Last updated